I am a neurologist treating disorders of brain, spinal cord and nerves. I like educating public and doctors about various aspects of neurological illnesses. This blog is an attempt towards the same. I work at Apollo Hospitals, (Jubilee Hills and Kukatpally branches), Hyderabad (phone-0091-40-23607777/60601066/9618204512; email@example.com)
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Friday, July 8, 2016
MEDICINES FOR TREATING ACIDITY COULD INCREASE THE RISK OF DEMENTIA
COMMONLY USED MEDICINES FOR ACIDITY INCREASE THE RISK OF DEMENTIA
Dementia is a condition, characterised by progressive loss of memory and other higher brain functions. It is a common cause of disability and dependence on others in older people.
Alzheimer's disease and brain stroke are the two most common causes of dementia.
1. In a recent research, medicines commonly used for treating acidity, were found to increase the risk of developing dementia in older people.
2. The effect of medicines belonging to the group of proton pump inhibitors (PPIs) such as omeprazole (omez), pantoprazole (pantodac, pantocid), rabeprazole (razo) were studied.
3. The study population included about 74,000 people from Germany, aged 75 or more.
4. People on regular prescriptions of PPIs (anti-acidity medications) had a significantly higher risk of developing dementia.
5. The possible mechanism is an increase in beta-amyloid in brain (which are involved in causing Alzheimer's disease).
This study was published in JAMA Neurology (April 2016), and those interested in reading further details of the study can access it at the following link: